副教授-副研究员-高级工程师

李德富

发布时间 :2018年07月12日      阅读量:

个人情况:

李德富,工学博士,副教授,硕士生导师

通讯地址:四川大学化学工程学院

邮编:610065

邮箱:lidefu@scu.edu.cn

教育和工作经历:

1998/09-2001/07,山东省临沂市第一中学,高中

2001/09-2005/07,四川大学,化学工程学院制药与生物工程系,大学本科/学士学位

2005/09-2010/07,四川大学,化学工程学院制药与生物工程系,硕博连读研究生/博士学位

2010/07-2014/06,四川大学,化学工程学院制药与生物工程系,讲师

2013/12-至今四川大学,化学工程学院生物化工专业,硕士生导师

2014/07-至今 四川大学,化学工程学院制药与生物工程系,副教授

社会工作:

2012/08-2013/07,江苏省委组织部“科技镇长团”成员,江苏省镇江市丹徒区宜城街道党工委,副书记

科学研究

研究方向:

天然高分子的化学改性;生物质化学与材料

承担科研项目:

1.纳米粘土改性胶原蛋白塑料的结构与性能.四川大学青年教师科研启动基金,2011.1-2012.12,项目负责人;

2. Brookfield粘度计功能的深度开发及在大学生创新实验中的应用.四川大学实验技术立项项目,2011.11-2012.11,项目负责人;

3.生物工程专业课程探究式教学方式的改革与实践.四川省“高等教育质量工程”建设项目,2012-2015,负责人;

4.纳米粘土在胶原蛋白塑料中的剥离行为及诱导作用研究.国家自然科学基金青年基金,2013.1-2015.12,项目负责人;

5.活性有机蒙脱土在胶原蛋白中的剥离行为及诱导作用研究.高等学校博士学科点专项科研基金,2013.1-2015.12,项目负责人;

6.一种功能性明胶粉条及其制备方法,企业委托,2014.4-2019.4,项目负责人;

7.醛多糖改性胶原蛋白塑料的微相分离行为研究.四川大学优秀青年学者科研基金,2015.1-2017.12,项目负责人;

8. 2016年度“化工之星”优秀青年人才培养计划,项目负责人;

9.异构双层自愈合胶原基骨缺损屏障膜的构筑及性能研究.四川省国际科技创新合作/港澳台科技创新合作项目. 2019.01-30-2020.12,项目负责人。

获奖及发明专利

获奖:

1. 2012年度四川大学教学成果奖二等奖,2017年度四川大学教学成果奖二等奖;

2.四川大学2011届、2013届、2014届、2016届、2017届本科优秀毕业论文指导教师;

3. 2013年度、2018年度四川大学课堂教学质量优秀奖;

4. 2014年度四川大学青年骨干教师奖;

5. 2014-2015学年四川大学学术型社团优秀指导教师二等奖,2015-2016学年学术型社团优秀指导教师优秀奖;

6. 2015中国化工学会年会优秀论文奖;

7.四川大学化学工程学院2016年优秀共产党员,四川大学化学工程学院2018年优秀党务工作者;

8.四川大学2017年、2018年大学生创新创业教育优秀指导教师;

9. 2019年第五届中国“互联网+”大学生创新创业大赛银奖指导教师;

10. 2019年四川省第五届“互联网+”学生创新创业大赛金奖指导教师;

11.四川省2019年第五届“互联网+”学生创新创业大赛优秀创新创业导师奖;

12.四川大学2019年第五届“互联网+”大学生创新创业大赛一等奖指导教师;

13. 2019年第五届全国大学生制药工程设计竞赛二等奖指导教师等荣誉称号。

第一发明人申请发明专利

1.一种功能性明胶粉条及其制备方法.中国发明专利,专利号:ZL201010119060.7

2.一种纳米复合材料中纳米粘土的冷冻分散方法.中国发明专利,专利号:ZL201110130461.7

3.一种酚酸类改性胶原蛋白面膜及其制备方法.中国发明专利,专利号:ZL201110309522.6

4.一种II型胶原和硫酸软骨素的综合提取工艺.中国发明专利,专利号:ZL201210196922.5

5.一种废水中阳离子染料吸附剂及其制备方法.中国发明专利,专利号:ZL201210482472.6

6.一种明胶基纳米复合材料及其制备方法.中国发明专利,专利号:ZL201210528098.9

7.一种功能性明胶食品包装膜及其制备方法.中国发明专利,专利号:ZL201510137884.X

8.一种纳米复合大豆蛋白塑料及其制备方法.中国发明专利,专利号:ZL201510304629.X

9.一种纳米银复合胶原医用敷料及其制备方法.中国发明专利,专利号:ZL201710115523.4

10.一种孔道结构可控的明胶细胞支架及其制备方法.中国发明专利,申请号:201810001229.5

发表论文

42.Lei Deng, Xinying Li, Keyan Miao, Xinyan Mao, Miao Han,Defu Li, Changdao Mu, Liming Ge*. Development ofdisulfide bondcrosslinkedgelatin/ε-polylysine active edible film with antibacterial and antioxidant activities.Food and Bioprocess Technology,2020,13, 577–588

41.Xi Zhao, Xinying Li, Xiaofen Xie, Jinfeng Lei, Liming Ge,* Lun Yuan,Defu Li,*Changdao Mu. Controlling the Pore Structure of Collagen Sponge by Adjusting the Crosslinking Degree for Construction of Heterogeneous Double-Layer Bone Barrier Membrane.ACS Applied Bio Materials, 2020,2020, 3, 2058−2067

40. Yongbin Xu, Yaxin Zi, Jinfeng Lei, Xingyue Mo, Zilun Shao, Yuyao Wu, Ye Tian,*Defu Li,* Changdao Mu. pH-Responsive nanoparticles based on cholesterol/imidazole modified oxidized-starch for targeted anticancer drug delivery.Carbohydrate Polymers, 2020, 233, 115858

39. Yongbo Lyu, Mengchao Yu, Qisong Liu, Qingmei Zhang, Zhanhong Liu, Ye Tian*,Defu Li*, Changdao Mu. Synthesis of silver nanoparticles using oxidized 1 amylose and combination with curcumin for enhanced antibacterial activity.Carbohydrate Polymers, 2020, 230, 115573

38. Mingjin Zhu, Xinying Li,*, Liming Ge, Yaxin Zi, Man Qi, Yulin Li,Defu Li*, Changdao Mu. Green synthesis of κ-carrageenan@Ag submicron-particles with high aqueous stability, robust antibacterial activity and low cytotoxicity.Materials Science & Engineering C, 2020, 106, 110185-110194

37. Xinyan Mao, Xinying Li,Wenjie Zhang,Lun Yuan,Lei Deng,Liming Ge, Changdao Mu, andDefu Li*. Development of Microspheres Based on Thiol-Modified Sodium Alginate for Intestinal-Targeted Drug Delivery.ACS Applied Bio Materials, 2019, 2, 5810−5818

36. Jinfeng Lei, Xinying Li, Shen Wang, Lun Yuan, Liming Ge,Defu Li*, Changdao Mu. Facile Fabrication of Biocompatible Gelatin-Based Self-Healing Hydrogel.ACS Applied Polymer Materials, 2019, 1, 1350−1358

35.韩淼,李德荣,袁柳青,吕永博,葛黎明,李德富,穆畅道.双醛淀粉还原制备纳米银及其在胶原基抗菌敷料中的应用.高分子学报, 2019, 50(4), 366-374

34. Lun Yuan, Xinying Li, Liming Ge, Xiaoqi Jia,Jinfeng Lei, Changdao Mu, andDefu Li*. Emulsion Template Method for the Fabrication of Gelatin-Based Scaffold with a Controllable Pore Structure.ACS Applied Materials & Interfaces, 2019, 11, 269−277.

33. Jinfeng Lei, Meizhou Zhang, Shen Wang, Lei Deng,Defu Li*, and Changdao Mu*.One-Pot Approach for the Synthesis of Water-Soluble Anatase TiO2Nanoparticle Cluster with Efficient Visible Light Photocatalytic Activity.The Journal of Physical Chemistry C,2018,122(46), 26447–26453.

32. Jinfeng Lei, Lei Deng, Xinying Li, Yongbin Xu,Defu Li*, Changdao Mu*. Comparative study of the physicochemical and photocatalytic properties of water-soluble polymer-capped TiO2nanoparticles.Environmental Science and Pollution Research, 2018, 25, 26259–26266.

31.梁伟杰,吕永博,穆畅道,李德富*.高性能正辛酸塑化明胶膜的热压法制备与表征.皮革科学与工程, 2018, 28(3), 11-19.

30. Liming Ge, Yongbin Xu, Xinying Li, Lun Yuan, Huan Tan,Defu Li*,Changdao Mu. Fabrication of Antibacterial Collagen-Based Composite Wound Dressing.ACS Sustainable Chemistry and Engineering.2018,6(7), 9153–9166.

29. He Ren, Yongbo Lyu, Xinying Li, Shuxiao Zhang, Yusong Ye,Defu Li*, Changdao Mu*.Preparation and characterization of dialdehyde β-cyclodextrin with broad-spectrum antibacterial activity.Food Research International, 2018, 111, 237-243.

28. Liming Ge, Mingjin Zhu, Xinying Li, Yongbin Xu*, Xiaonan Ma, Rong Shi,Defu Li*, Changdao Mu. Development of active rosmarinic acid-gelatin biodegradable films with antioxidant and long-term antibacterial activities.Food Hydrocolloids, 2018, 83, 308-316.

27. Yaxin Zi, Mingjin Zhu, Xinying Li, Yongbin Xu, Hao Wei,Defu Li*,Changdao Mu*. Effects of carboxyl and aldehyde groups on the antibacterial activity of oxidized amylose.Carbohydrate Polymers192 (2018) 118-125.

26.訾娅鑫,雷金凤,徐志朗,李德富*,穆畅道*.多糖的氧化改性及在生物医药领域的应用.生物加工过程, 2018, 16(1): 31-37 (优秀生物化工青年学者专刊)

25. Youxin Ye, He Ren, Shu Zhu, Huan Tan, Xinying Li*,Defu Li*, Changdao Mu. Synthesis of oxidized β-cyclodextrin with high aqueous solubility and broad-spectrum antimicrobial activity.Carbohydrate Polymers, 2017, 177: 97-104.

24. Yongbo Lyu, He Ren, Mengchao Yu, Xinying Li,Defu Li*, Changdao Mu*.Using oxidized amylose as carrier of linalool for the development of antibacterial wound dressing.Carbohydrate Polymers, 2017, 174, 1095–1105

23. Mingjin Zhu, Liming Ge, Yongbo Lyu, Yaxin Zi, Xinying Li*,Defu Li*, Changdao Mu.Preparation, characterization and antibacterial activity of oxidizedκ-carrageenan.Carbohydrate Polymers, 2017, 174, 1051–1058.

22.Youxin Ye, Mingjin Zhu, Keyan Miao, Xinying Li*,Defu Li*, Changdao Mu.Development of antimicrobial gelatin-based edible films by incorporation oftrans-anethole/β-cyclodextrin inclusion complex.Food and Bioprocess Technology,2017, 10(10): 1844–1853.

21. Liming Ge, Mingjin Zhu, Yongbin Xu, Xinying Li*,Defu Li*, Changdao Mu.Development of antimicrobial and controlled biodegradable gelatin-based edible films containing nisin and amino-functionalized montmorillonite.Food and Bioprocess Technology, 2017, 10:1727–1736

20.Meizhou Zhang, Jinfeng Lei, Yifeng Shi, Lina Zhang, Youxin Ye,Defu Li*, Changdao Mu*. Molecular weight effects of PEG on the crystal structure and photocatalytic activities of PEG-capped TiO2nanoparticles.RSC Advances, 2016, 6, 83366 - 83372

19. Ying Zhou, Youxin Ye, Wenwen Zhang, Songling Li, Jing Chen, Shiting Wang,Defu Li*, Changdao Mu*. Oxidized amylose with high carboxyl content: A promising solubilizer and carrier of linalool for antimicrobial activity.Carbohydrate Polymers, 2016, 154, 13-19.

18. Liming Ge, Yongbin Xu, Weijie Liang, Xinying Li*,Defu Li*, Changdao Mu. Short-range and long-range cross-linking effects of polygenipin on gelatin-based composite materials.Journal of Biomedical Materials Research: Part A, 2016, 104A: 2712–2722.

17.Defu Li*, Youxin Ye, Derong Li, Xinying Li, Changdao Mu*. Biological properties of dialdehyde carboxymethyl cellulose crosslinked gelatin-PEG composite hydrogel fibers for wound dressings.Carbohydrate Polymers, 2016, 137, 508-514.

16. Ying Zhou, Xinying Li, Yongbo Lv, Yifeng Shi, Yu Zeng,Defu Li*, Changdao Mu*. Effect of oxidation level on the inclusion capacity and solution stability of oxidized amylose in aqueous solution.Carbohydrate Polymers,2016, 138, 41-48.

15. Liming Ge, Xinying Li, Run Zhang, Tianhan Yang, Xiaowei Ye,Defu Li*, Changdao Mu.Development and characterisation of dialdehyde xanthan gum crosslinked gelatin based edible films incorporated with amino-functionalized montmorillonite.Food Hydrocolloids, 2015, 51, 129-135.

14. Wenwen Zhang, Xinying Li, Taocheng Yu, Lun Yuan, Gang Rao,Defu Li*, Changdao Mu*. Physicochemical and release characterisation of the inclusion complex of β-cyclodextrin andtrans-anethole.Food Research International, 2015, 74, 55-62.

13. Kechen Li, Jiangen Peng, Meizhou Zhang, Jian Heng,Defu Li*, Changdao Mu*. Comparative study of the effects of anatase and rutile titanium dioxide nanoparticles on the structure and properties of waterborne polyurethane.Colloids and Surfaces A: Physicochemical and Engineering Aspects,2015, 470, 92-99.

12. Jimin Guo, Liming Ge, Xinying Li, Changdao Mu,Defu Li*. Periodate oxidation of xanthan gum and its crosslinking effects on gelatin-based edible films.Food Hydrocolloids, 2014, 39, 243-250.

11. Xinying Li, Hongyan Ma, Huilian Huang,Defu Li, Shun Yao. Natural anthocyanins form phytoresources and their chemical researcher.Natural ProductResearch, 2013, 27(4-5): 456-469.

10. Changdao Mu, Ke Zhang, Wei Lin,Defu Li*.Ring-opening polymerization of genipin and its long-range crosslinking effect on collagen hydrogel.Journal of Biomedical Materials Research: Part A, 2013, 101A, 385-393.

9. Changdao Mu, Xinying Li, Yige Zhao, Hanguang Zhang, Liangjie Wang,Defu Li*.Freezing/thawing Effects on the Exfoliation of Montmorillonite in Gelatin-based Bionanocomposite.Journal of Applied Polymer Science, 2013, 128, 3141-3148.

8. Changdao Mu, Xinying Li, Jimin Guo, Caixia Bi,Defu Li*. Effects of Montmorillonite on the Structure and Properties of Gelatin-PEG Composite Fibers.Journal of Applied Polymer Science, 2013, 129, 773-778.

7. Jimin Guo, Xinying Li, Changdao Mu, Hanguang Zhang, Pan Qin,Defu Li*. Freezing-thawing effects on the properties of dialdehyde carboxymethyl cellulose crosslinked gelatin-MMT composite films.Food Hydrocolloids, 2013, 33, 273-279.

6. Changdao Mu, Jimin Guo, Xinying Li, Wei Lin,Defu Li*.Preparation and properties of dialdehyde carboxymethyl cellulose crosslinked gelatin edible films.Food Hydrocolloids, 2012, 27, 22-29. (ESI Top 1%高引用率论文)

5. Lirong He, Changdao Mu,Defu Li, Wei Lin.Revisit the pre-transition of type I collagen denaturation in dilute solution by ultrasensitive differential scanning calorimetry.Thermochimica Acta, 2012, 548, 1-5.

4. Dihan Su, Chunhua Wang, Sumei Cai, Changdao Mu,Defu Li, Wei Lin.Influence of palygorskite on the structure and thermal stability of collagen.Applied Clay Science, 2012, 62-63, 41-46.

3.Defu Li, Changdao Mu, Qian Zhang, Yuling Zhou, Wei Lin*. Effects of Microwave Irradiation on Collagen Denaturation.Journal of Food Biochemistry, 2010, 34, 1319-1331.

2.Defu Li, Changdao Mu, Cai Sumei, Wei Lin. Ultrasonicirradiation in the enzymatic extraction of collagen.Ultrasonics Sonochemistry, 2009, 16, 605-609.

1. Changdao Mu,Defu Li,Wei Lin, Yanwei Ding, and Guangzhao Zhang. Temperature induced denaturation of collagen in acidic solution.Biopolymers, 2007, 86(4), 282-287.




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