副教授-副研究员-高级工程师

黄文才

发布时间 :2018年07月12日      阅读量:

黄文才 副教授
四川大学 化工学院 制药与生物工程系
联系方式:成都市一环路南一段24号 四川大学化工学院 (邮编610065)
E-mail: hwc@scu.edu.cn

教育背景
1993. 9 -- 1997. 7   成都科技大学  有机化工专业  工学学士
1997. 9 -- 2000. 7   四川大学  应用化学专业  工学硕士
2000. 9 -- 2003. 7   四川大学  药物化学专业  理学博士

工作简历
2003. 9 -- 2005. 9   中科院上海药物研究所  博士后
2005. 10 -- 至今    四川大学  化工学院  制药与生物工程系  讲师/副教授/硕士生导师
2014. 9 -- 2015. 9   美国弗吉尼亚大学化学系  访问学者

教学工作
负责本科生《药物化学》和《化学制药工艺学》及研究生《原料药生产工艺开发》等课程的教学工作,主编和参编本科生教材各1本。

科研方向
1. 化学制药工艺研究
2. 药物研制与开发
3. 小分子荧光探针的研究
曾主持或参加国家自然科学基金、广东省-教育部产学研结合项目、四川大学校青年科研基金及多项企业合作开发项目。

代表性科研成果
1. Zhang Yi, Tu Liangping, Lu Lingling, Li Yuxiao, Song Linjiang,* Qi Qingrong, Song Hang, Li Zicheng, Huang Wencai*. Screening and application of boron difluoride complex of curcumin as a colorimetric and ratiometric fluorescent probe for bisulfite. Anal. Methods, 2020, 12(11), 1514-1521.
2. Liu Jian, Li Tao, Wang Shun, Qi Qingrong, Song Hang, Li Zicheng, Yang Li*, Huang Wencai*. A sensitive and selective fluorescent probe for hydrazine with a unique nonaromatic fluorophore. RSC Adv., 2020, 10, 5572-5578.
3. Li Tao, Liu Jian, Song Linjiang, Li Zicheng, Qi, Qingrong*, Huang Wencai*. A hemicyanine-based fluorescent probe for hydrazine detection in aqueous solution and its application in real time bioimaging of hydrazine as a metabolite in mice. J. Mater. Chem. B, 2019, 7, 3197-3200.
4. Li Yuan, Ji Yu-Xin, Song Lin-Jiang, Zhang Yi, Li Zi-Cheng, Yang Li, Huang Wen-Cai*. A novel BF2-curcumin-based fluorescent chemosensor for detection of Cu2+ in aqueous solution and living cells. Res. Chem. Intermed., 2018, 44(9), 5169-5180.
5. Zhou Ji-Cai, Zhao Lei, Li Yuan, Fu Ding-Qiang, Li Zi-Cheng, Huang Wen-Cai*. Alkynylation of aldehydes mediated by Zinc and allyl bromide: a practical synthesis of propargylic alcohols. Res. Chem. Intermed., 2017, 43(7), 4283-4294.
6. Zhang Yun-Hao, Wu Ming-Yue, Huang Wen-Cai*. Silica gel-promoted practical synthesis of oxindole-nitrones from diazooxindoles and nitrosoarenes under solvent-free conditions. RSC Adv., 2015, 5(128), 105825-105828.
7. Huang Wen-Cai, Liu Winnie, Wu Xue-Dan, Ying Jun, Pu Lin*. Highly enantioselective alkyne addition to aliphatic, aromatic and vinyl aldehydes by using Zn, iPrI, H8BINOL and Ti(OiPr)4. J. Org. Chem., 2015, 80(22), 11480-11484.
8. Xie J. Y., Liu J. Q., Zhang Y. H., Li J. J., Li Z. C., Huang W. C.*. An improved preparation of 2, 6-di-tert-butyl-4-methylphenol. Org. Prep. Proced. Int., 2015, 47(3), 236-241.
9. Liu Junqiang, Mi Chenggen, Tang Xuemei, Cao Yuan, Li Zicheng, Huang Wencai*. Facile microwave-assisted synthesis of substituted benzofuran derivatives. Res. Chem. Intermed., 2014, 40(5), 2083-2090.
10. Yang Li, Lei Hua, Mi Cheng-Gen, Liu Huan, Zhou Tian, Zhao Ying-Lan, Lai Xiao-Yun, Li Zi-Cheng, Song Hang, Huang Wen-Cai*. Synthesis, antiproliferative activities and in vitro biological evaluation of novel benzofuransulfonamide derivatives. Bioorg. Med. Chem. Lett., 2011, 21(18), 5389-5392.
11. Luo Xin-Feng, He Ling, Yin Hai-Bin, Zheng Hu, Bei Di, Deng Jin-Jin, Huang Wen-Cai*. Efficient acylation and one-pot synthesis of dehydroandrographolide succinate on a large scale assisted with microwave radiation. Synth. Commun., 2009, 39(19), 3444-3452.
12. Huang Wencai, Zheng Hu, Weng Lingling. Synthesis of tetracycline analogs and their bone affinities. Chin. Chem. Lett., 2008, 19(1), 19-22.
13. 黄文才, 张丹, 程度, 张春红, 陈文芝, 雷华. 一种三水合3-氨基丙基胺乙基硫代磷酸的合成方法. 中国发明专利, ZL 201110152336.6, 2014-2-26.




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